SLAP1 Polyclonal Antibody, 50ul Serological Pipets and a hydrophobic protein (HP)

and a hydrophobic protein (HP) fraction

Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25

The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members

Two transcript variants encoding distinct isoforms have been found for this gene

Disruption of this gene may be associated with cerebral palsy

SLAP1 Polyclonal Antibody, 50ul Serological Pipets and a hydrophobic protein (HP)The C terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization.,Adapter protein, which negatively regulates T cell receptor (TCR) signaling. Inhibits T cell antigen receptor induced activation of nuclear factor of activated T cells. Involved in the negative