Moesin/Ezrin/Radixin(Phospho Thr558) Polyclonal Antibody, 20ul Dry Bath PTTG1 product has transforming activity

PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo

Mutations in this gene result in incontinentia pigmenti| hypohidrotic ectodermal dysplasia| and several other types of immunodeficiencies

p38/MAPK14

it is activated by the anesthetics halothane and isoflurane

The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase

Moesin/Ezrin/Radixin(Phospho Thr558) Polyclonal Antibody, 20ul Dry Bath PTTG1 product has transforming activityMoesin (for membrane organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross linkers between plasma membranes and actin based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell cell recognition and signaling and for cell movement.