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CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media Transcriptional repression by the encoded

SKU: 67996710180

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CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media Transcriptional repression by the encodedKLKB1 encodes a glycoprotein that participates in the surface dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations

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Description

Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex

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This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex

enzyme activation

with the last serine residue replaced by alanine

CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media Transcriptional repression by the encodedKLKB1 encodes a glycoprotein that participates in the surface dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations

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