Manic Fringe Polyclonal Antibody, 100ul Shakers Increases firing activity and intracellular

Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons

this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B)

RNA editing is predicted to alter the structure of the second intracellular loop

Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes

miscellaneous:Two forms have been identified in animal cells

Manic Fringe Polyclonal Antibody, 100ul Shakers Increases firing activity and intracellularMFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked