Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression The beta subunit contains a

The beta subunit contains a C-terminal domain which is involved in cell signaling

It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines| suggesting that it may play a role in lung tumorigenesis

cleaves SPHK2 which is released from cells and remains enzymatically active extracellularly

Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis

Component of RNA polymerase I which synthesizes ribosomal RNA precursors

Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression The beta subunit contains aSeems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.