Tra-2 Alpha Polyclonal Antibody, 50ul Lentiviral Packaging These autoantibodies are present in

These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC)

They may participate in fatty acyl and cholesterol ester metabolism

subunit:Member of the pointed-end complex of the dynactin shoulder complex which contains DCTN4

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable)| together with a carnitine-acylcarnitine translocase

the strongest expression is found in the tunica media of the proximal ascending aorta

Tra-2 Alpha Polyclonal Antibody, 50ul Lentiviral Packaging These autoantibodies are present inTRA2A is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre mRNA splicing. Alternatively spliced transcript variants have been found for this gene.