RGL1 Polyclonal Antibody, 100ul Organelle Studies The encoded protein negatively regulates

The encoded protein negatively regulates wingless/integrated signaling through interaction with the post synaptic density protein/ Drosophila disc large tumor suppressor/ zonula occludens-1 protein domain of Dishevelled| a scaffolding protein required for the stabilization of the transcriptional co-activator beta-catenin

Phosphorylation of Tyr-358 is involved in binding to PTPN6

the immune response

The encoded protein contains a 7-transmembrane receptor domain

Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1

RGL1 Polyclonal Antibody, 100ul Organelle Studies The encoded protein negatively regulatesProbable guanine nucleotide exchange factor.,Contains 1 N terminal Ras GEF domain.,Contains 1 Ras associating domain.,Contains 1 Ras GEF domain.,subunit: Interacts with Ras.,tissue specificity: Expressed in a wide variety of tissues with strong expression being seen in the heart, brain, kidney, spleen and testis.,