TM199 Rabbit Polyclonal Antibody, 100ul Mammalian Expression c-IAP1 is thought to potentiate

c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2

thus targeting specific proteins for lysosomal degradation

The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes

TIRP is a Toll/interleukin-1 receptor (IL1R

The C-terminus of this protein is divergent from that of its chromosome X homolog (TGIF2LX)

TM199 Rabbit Polyclonal Antibody, 100ul Mammalian Expression c-IAP1 is thought to potentiateThe protein encoded by this gene has been observed to localize to the endoplasmic reticulum (ER) Golgi intermediate compartment (ERGIC) and coat protein complex I (COPI) in some human cells. The encoded protein shares some homology with the yeast protein Vma12. Defects in this gene are a cause of congenital disorder of glycosylation type IIp.