Tuberin Polyclonal Antibody, 20ul[BT-AP09287] Microbial Genome Editing POLR3B (RNA polymerase III subunit

POLR3B (RNA polymerase III subunit B) encodes the second largest subunit of RNA polymerase III

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including neuronal migration and differentiation

This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG

Produced in Class 100

Tuberin Polyclonal Antibody, 20ul[BT-AP09287] Microbial Genome Editing POLR3B (RNA polymerase III subunitMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.