Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis and susceptibility to Legionnaire disease

and susceptibility to Legionnaire disease

The interaction with ERC1 may be mediated by PHLDB2

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A

Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis and susceptibility to Legionnaire diseaseVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.