CD59 Polyclonal Antibody, 100ul[BT-AP02408] Centrifugal Filter Methylated-DNA--protein-cysteine methyltransferase encoded by MGMT

Methylated-DNA--protein-cysteine methyltransferase encoded by MGMT is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents

|PTM:TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products

This gene product was shown to bind single-stranded DNA ends

The recognition component of this pathway

Congenital

CD59 Polyclonal Antibody, 100ul[BT-AP02408] Centrifugal Filter Methylated-DNA--protein-cysteine methyltransferase encoded by MGMTCYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cytochrome P450 2D6 localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta