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UHRF1 Monoclonal Antibody, 50ul Mechanical Pipette EID-1 inhibits cellular differentiation by

SKU: 6538189313

4.7
PLN185.00 PLN231.00

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UHRF1 Monoclonal Antibody, 50ul Mechanical Pipette EID-1 inhibits cellular differentiation byThis gene encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent DNA damage

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Description

EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300

Alternatively spliced transcript variants have been found for this locus

and also dominant nonimmune chronic idiopathic neutropenia of adults

spinocerebellar ataxia type 6

ATF5 plays a role in inhibition of nerve growth factor induced neuronal outgrowth and regulation of neurogenesis

UHRF1 Monoclonal Antibody, 50ul Mechanical Pipette EID-1 inhibits cellular differentiation byThis gene encodes a member of a subfamily of RING finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1 S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53 dependent DNA damage

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