CLCN5 Polyclonal Antibody, 50ul Sealing Film Multiple transcript variants encoding two

Multiple transcript variants encoding two different isoforms were identified through sequence analysis

This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase

belongs to the BAGE family

an event that can trigger a protein-protein interaction cascade which may ultimately effect gene expression and cellular function

pre-mRNA-splicing regulator WTAP is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors

CLCN5 Polyclonal Antibody, 50ul Sealing Film Multiple transcript variants encoding twoThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.