APLP-1 Polyclonal Antibody, 100ul Thermal Control In migrating cells

In migrating cells

Diseases associated with PRDM12 include neuropathy

Although there is no evidence of transcription from this pseudogene

An important paralog of this gene is HAP1

Alternatively spliced transcript variants encoding multiple isoforms have been observed for SLC9A3R2

APLP-1 Polyclonal Antibody, 100ul Thermal Control In migrating cellsAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.