KMT1B Polyclonal Antibody, 20ul Cellular Function Assays Mutations in this gene are

Mutations in this gene are associated with several congenital defects

Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN

These exonucleases include the family of DNA polymerases

Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity)

GRB10 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors

KMT1B Polyclonal Antibody, 20ul Cellular Function Assays Mutations in this gene areHistone lysine N methyltransferase SUV39H2 is a Histone methyltransferase that specifically trimethylates Lys 9 of histone H3 using monomethylated H3 Lys 9 as substrate. H3 Lys 9 trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive