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LIS1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Acts on acids from C(4)

SKU: 63845286986

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EUR97.20 EUR138.20

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LIS1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Acts on acids from C(4)This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller Dieker lissencephaly syndrome. This gene encodes the non catalytic alpha subunit of the intracellular Ib isoform of platelet activating factor acteylhydrolase a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN 2 position of platelet activating factor (identified as 1 O alkyl 2 acetyl sn

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Description

Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2

Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin

Since this protein is not capable of binding DNA directly

Among its related pathways are Cell adhesion_Endothelial cell contacts by junctional mechanisms

Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin

LIS1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Acts on acids from C(4)This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller Dieker lissencephaly syndrome. This gene encodes the non catalytic alpha subunit of the intracellular Ib isoform of platelet activating factor acteylhydrolase a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN 2 position of platelet activating factor (identified as 1 O alkyl 2 acetyl sn

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