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p300 Polyclonal Antibody, 50ul[BT-AP06773] Cell Function Analysis GTPases of the RAB family

SKU: 63732578141

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p300 Polyclonal Antibody, 50ul[BT-AP06773] Cell Function Analysis GTPases of the RAB familyEP300 (E1A binding protein p300) encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia

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Description

GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments

This gene encodes a nuclear-localized E3 ubiquitin ligase

This gene has been found fused to a variety of translocation partner genes in various leukemias

It phosphorylates the eukaryotic initiation factor 4E (eIF4E)

There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591)

p300 Polyclonal Antibody, 50ul[BT-AP06773] Cell Function Analysis GTPases of the RAB familyEP300 (E1A binding protein p300) encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia

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