LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges this mRNA is expressed only

this mRNA is expressed only in testis

the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription

and it is found in the mitochondrial intermembrane space in healthy cells

The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases

This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges this mRNA is expressed onlyThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative