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p27(Phospho Thr187) Polyclonal Antibody, 100ul Protein Post-translational Modification APOL3 (apolipoprotein L3) is a

SKU: 63654008758

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p27(Phospho Thr187) Polyclonal Antibody, 100ul Protein Post-translational Modification APOL3 (apolipoprotein L3) is aThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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Description

APOL3 (apolipoprotein L3) is a member of the apolipoprotein L gene family

in a block of sequence that is thought to be the result of a large X-to-Y transposition

osteopontin

contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases

Molecular switching by diphosphoinositol polyphosphates may contribute to the regulation of intracellular trafficking

p27(Phospho Thr187) Polyclonal Antibody, 100ul Protein Post-translational Modification APOL3 (apolipoprotein L3) is aThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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