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PP4R2 Polyclonal Antibody, 20ul Hepatocytes an autosomal dominant pre-malignant disease

SKU: 63326756082

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PP4R2 Polyclonal Antibody, 20ul Hepatocytes an autosomal dominant pre-malignant diseaseSerine threonine protein phosphatase 4 regulatory subunit 2 encoded by PPP4R2 is a regulatory subunit of the serine threonine protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene.

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Description

an autosomal dominant pre-malignant disease that usually progresses to malignancy

Multiple transcript variants have been identified

as well as to the cell membrane

The encoded protein is part of a DNA-binding transcription complex

which was isolated and identified based on its enzymatic activity and amino acid sequence

PP4R2 Polyclonal Antibody, 20ul Hepatocytes an autosomal dominant pre-malignant diseaseSerine threonine protein phosphatase 4 regulatory subunit 2 encoded by PPP4R2 is a regulatory subunit of the serine threonine protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene.

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