NPBW2 Polyclonal Antibody, 20ul Cell Separation and Collection Mutations in this gene are

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

There are numerous pseudogenes of this gene distributed throughout the genome

The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13

Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain

The cAMP regulated phosphoprotein 21 is enriched in the caudate nucleus and cerebellar cortex

NPBW2 Polyclonal Antibody, 20ul Cell Separation and Collection Mutations in this gene areThe protein encoded by this gene is an integral membrane protein and G protein coupled receptor. The encoded protein is similar in sequence to another G protein coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain.