Rat Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Contamination Detection & Removal Binding to cell surface proteoglycans

Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites

The PAT complex acts as an intramembrane chaperone by directly interacting with nascent transmembrane domains (TMDs)

and commonly used as a molecular tag to study protein localization

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

culture flasks

Rat Atp-binding Cassette Sub-family G Member 5, ABCG5 ELISA Kit, 96T Contamination Detection & Removal Binding to cell surface proteoglycansABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity.