PTEN(Phospho Ser370) Polyclonal Antibody, 20ul Serological Pipets Mutations in this gene can

Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia

recessive deafness

The interaction of this PTP with BMX kinase was found to increase the activation of STAT3

BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities

Multiple alternatively spliced transcript variants have been reported for this gene

PTEN(Phospho Ser370) Polyclonal Antibody, 20ul Serological Pipets Mutations in this gene canThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide