CDX2 Monoclonal Antibody(14H6), 20ul PCR Series 11) chromosomal translocation involving this

11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

UBE2D2 encodes a member of the E2 enzyme family

The amyloid-like protein 1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage

suggesting that the function of this gene may be signal repression

It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues

CDX2 Monoclonal Antibody(14H6), 20ul PCR Series 11) chromosomal translocation involving thisThis gene is a member of the caudal related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.