UPAR Rabbit Polyclonal Antibody, 20ul Live Cell Imaging with defects in NPY5R being

with defects in NPY5R being associated with eating disorders

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

Contains 1 IRS-type PTB domain

This protein localizes to the extracellular matrix

The encoded protein has been shown to interact with the cancer developmental regulators SMAD2

UPAR Rabbit Polyclonal Antibody, 20ul Live Cell Imaging with defects in NPY5R beingActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.