TNNC2 Polyclonal Antibody, 20ul Gene Editing NOTCH2 encodes a member of

NOTCH2 encodes a member of the NOTCH family

The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor

Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect

This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum

This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet

TNNC2 Polyclonal Antibody, 20ul Gene Editing NOTCH2 encodes a member ofTroponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn I subunit inhibits actomyosin ATPase, the Tn T subunit binds tropomyosin and Tn C, while the Tn C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn C subunit.