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HECW1 Polyclonal Antibody, 50ul Antibodies The length and aperture of

SKU: 61289660445

4.9
USD162.00 USD210.00

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HECW1 Polyclonal Antibody, 50ul Antibodies The length and aperture ofE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

The length and aperture of the tube can also be customized

The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol

This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development

Together with PCBP-1

TBL2 is deleted in Williams-Beuren syndrome

HECW1 Polyclonal Antibody, 50ul Antibodies The length and aperture ofE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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