UBE4A Polyclonal Antibody, 100ul Cellular Function Assays MIM 607393)| CTR9 (MIM 609366)|

MIM 607393)| CTR9 (MIM 609366)| and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al

The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome

Undetectable in other tissues

It possesses histone deacetylase activity and represses transcription when tethered to a promoter

which are important in RNA binding and are known to be involved in RNA synthesis and metabolism

UBE4A Polyclonal Antibody, 100ul Cellular Function Assays MIM 607393)| CTR9 (MIM 609366)|UBE4A encodes a member of the U box ubiquitin ligase family. The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants