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Phospho-Caspase-2 (S157) Polyclonal Antibody, 100ul Serological Pipets Repressor that binds to DNA

SKU: 61140685113

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Phospho-Caspase-2 (S157) Polyclonal Antibody, 100ul Serological Pipets Repressor that binds to DNACASP2 (caspase 2) encodes a member of the cysteine aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease

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Description

Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides

GO annotations related to this gene include sodium channel activity and ligand-gated sodium channel activity

Myc is an oncoprotein implicated in cell proliferation

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors

Mutations in ANKRD26 are associated with autosomal dominant thrombocytopenia-2

Phospho-Caspase-2 (S157) Polyclonal Antibody, 100ul Serological Pipets Repressor that binds to DNACASP2 (caspase 2) encodes a member of the cysteine aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of CASP2 may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease

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