syntenin Rabbit Polyclonal Antibody, 20ul Molecular Biology The encoded protein regulates signaling

The encoded protein regulates signaling pathways that affect cell proliferation and adhesion

The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II)| which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation

The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al

but further studies have shown that TWEAK could induce apoptosis via receptors distinct from DR3

Pseudogenes of PRKX are found on chromosomes X

syntenin Rabbit Polyclonal Antibody, 20ul Molecular Biology The encoded protein regulates signalingThe protein encoded by this gene was initially identified as a molecule linking syndecan mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic C terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal membrane organization cell adhesion protein trafficking and the activation of transcription factors. The protein is primarily localized to