Rat Neurogenic Locus Notch Homolog Protein 1, NOTCH1 ELISA Kit, 96T Bio-Reaction Tube Cell surface receptor for LCN2

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport

subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo

The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras

The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix

The protein positively regulates the downstream effector ribosomal protein S6 kinase| and negatively regulates the mTOR kinase

Rat Neurogenic Locus Notch Homolog Protein 1, NOTCH1 ELISA Kit, 96T Bio-Reaction Tube Cell surface receptor for LCN2Functions as a receptor for membrane bound ligands Jagged 1 (JAG1), Jagged 2 (JAG2) and Delta 1 (DLL1) to regulate cell fate determination (By similarity). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ RBPSUH and activates genes of the enhancer of split locus (By similarity). Affects the implementation of differentiation, proliferation and apoptotic programs (By