JIP-1(Phospho Thr103) Polyclonal Antibody, 100ul Aspirating Pipets |Transcriptional activator which triggers apoptosis

|Transcriptional activator which triggers apoptosis in the absence of survival factors| including neuronal cell death upon oxidative stress

Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination

This gene encodes a member of the low-density lipoprotein receptor related protein family

In the rest of the brain a basal expression seems to be always present

In aldosterone-selective epithelial tissues such as the kidney

JIP-1(Phospho Thr103) Polyclonal Antibody, 100ul Aspirating Pipets |Transcriptional activator which triggers apoptosisThis gene encodes a regulator of the pancreatic beta cell function. It is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA binding transactivator of the glucose