N2DL3 Polyclonal Antibody, 20ul Variant Libraries The 3-hydroxyisobutyrate dehydrogenase plays a

The 3-hydroxyisobutyrate dehydrogenase plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde

Alternatively spliced transcript variants have been found for KRT8

MIM 612725) (Stefansson and Brautigan| 2006

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs)

This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells

N2DL3 Polyclonal Antibody, 20ul Variant Libraries The 3-hydroxyisobutyrate dehydrogenase plays aThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.