Filamin 1(Phospho Ser2152) Polyclonal Antibody, 50ul Insect Expression This gene is a member

This gene is a member of the iron/manganese superoxide dismutase family

Widely expressed in myeloid leukemia cell lines

The zona pellucida glycoprotein 1 encoded by ZP1 ensures the structural integrity of the zona pellucida

The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location

Alternative splicing has been observed at this locus and three variants

Filamin 1(Phospho Ser2152) Polyclonal Antibody, 50ul Insect Expression This gene is a memberThe protein encoded by this gene is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias