ASPP2 Polyclonal Antibody, 100ul Funnels Defects in ACTA2 cause aortic

Defects in ACTA2 cause aortic aneurysm familial thoracic type 6

Mutations in TH have been associated with autosomal recessive Segawa syndrome

which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB

The protein encoded by SLC6A11 (solute carrier family 6 member 11) is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA)

The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10

ASPP2 Polyclonal Antibody, 100ul Funnels Defects in ACTA2 cause aorticThis gene encodes a member of the ASPP (apoptosis stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different