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DBLOH Polyclonal Antibody, 50ul Filtration The Ser/Thr protein kinase encoded

SKU: 5969892054

4.2
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DBLOH Polyclonal Antibody, 50ul Filtration The Ser/Thr protein kinase encodedThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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Description

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily

tissue specificity:Expressed in lung fibroblasts

13) family

This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons

Contains 1 B30

DBLOH Polyclonal Antibody, 50ul Filtration The Ser/Thr protein kinase encodedThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript

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