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Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology This gene location is also

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Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology This gene location is alsoBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia

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Description

This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3)

This protein mediates the expression of a variety of genes in response to cell stimuli| and thus plays a key role in many cellular processes such as cell growth and apoptosis

This protein is not restricted to leukemic cells

Related pseudogenes have been found on chromosomes 3 and 14

Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor

Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology This gene location is alsoBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia

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