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TRPM2 Rabbit Polyclonal Antibody, 50ul 3D Cell Culture Consumables Mutations in this gene are

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TRPM2 Rabbit Polyclonal Antibody, 50ul 3D Cell Culture Consumables Mutations in this gene areThe protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium sodium and potassium and is regulated by free intracellular ADP ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described but their full length nature is

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Description

Mutations in this gene are associated with nail-patella syndrome

This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis

Ser-1029 or Ser-1031 is important for cytoplasmic export

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TRPM2 Rabbit Polyclonal Antibody, 50ul 3D Cell Culture Consumables Mutations in this gene areThe protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium sodium and potassium and is regulated by free intracellular ADP ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described but their full length nature is

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