F105B Rabbit Polyclonal Antibody, 20ul Roller Bottles A related pseudogene is located

A related pseudogene is located nearby on chromosome 6

Mutations in this gene cause primary ciliary dyskinesia type 3| as well as Kartagener syndrome| which are both diseases due to ciliary defects

and to a lesser degree

where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments

Among its related pathways are Platelet activation and Ras signaling pathway

F105B Rabbit Polyclonal Antibody, 20ul Roller Bottles A related pseudogene is locatedThis gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1) linked or linear ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory