GluR-2(Phospho-Tyr876) Polyclonal Antibody, 100ul Cell Labeling & Imaging SPTBN2 regulates the glutamate signaling

SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane

Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE)

Contains 1 G-patch domain

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF)

The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response

GluR-2(Phospho-Tyr876) Polyclonal Antibody, 100ul Cell Labeling & Imaging SPTBN2 regulates the glutamate signalingGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate (AMPA), and function as ligand activated cation channels. These channels are assembled from 4 related subunits, GRIA1 4. The subunit encoded by this