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CD58 Polyclonal Antibody, 50ul[BT-AP01550] Culture Media Defects in this gene have

SKU: 5837625485

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CD58 Polyclonal Antibody, 50ul[BT-AP01550] Culture Media Defects in this gene haveLILRB5 is a member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells

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Description

Defects in this gene have been linked to premature ovarian failure 2

that arises within the acrosomal vesicle during spermatogenesis

this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity

This leads to the eventual degradation of the substrate protein

a component of tissue and tumor stroma implicated as an inhibitor of tumor progression

CD58 Polyclonal Antibody, 50ul[BT-AP01550] Culture Media Defects in this gene haveLILRB5 is a member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells

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