CDC42 Polyclonal Antibody, 50ul Electronic Pipette The protein encoded by this

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5

This gene is overexpressed in colon tumors

The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme

This gene product interacts with the C-terminal domain of the DEXD/H-box helicase 58 (DDX58) gene product

contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases

CDC42 Polyclonal Antibody, 50ul Electronic Pipette The protein encoded by thisThe protein encoded by this gene is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein.