PIP5KIII Polyclonal Antibody, 100ul[BT-AP07184] Serum & Sample Tubes The protein encoded by this

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization

with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions

Elevated levels of this protein are found in patients with POEMS syndrome

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

increasing the rate of conversion of the GTP to GDP

PIP5KIII Polyclonal Antibody, 100ul[BT-AP07184] Serum & Sample Tubes The protein encoded by thisPhosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell and endosomal membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. PIKFYVE encodes an enzyme (PIKfyve; also known as phosphatidylinositol 3 phosphate 5 kinase type III or PIPKIII) that phosphorylates