PKC Delta Polyclonal Antibody, 100ul[BT-AP07216] ssDNA Synthesis Mutations in this gene cause

Mutations in this gene cause X-linked agammaglobulinemia type 1| which is an immunodeficiency characterized by the failure to produce mature B lymphocytes| and associated with a failure of Ig heavy chain rearrangement

leads to ciliary neurotrophic factor deficiency

TPCN1 is similar to these channels| but it has only 2 domains containing S1 to S6 (Ishibashi et al

The TRIM family is characterized by a signature motif composed of a RING finger| one or more B-box domains| and a coiled-coil region

There is an antisense transcript that overlaps on the opposite strand with this gene locus

PKC Delta Polyclonal Antibody, 100ul[BT-AP07216] ssDNA Synthesis Mutations in this gene causeProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile