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Puratrophin 1 Polyclonal Antibody, 100ul Protein Analysis it alters splicing of CD45

SKU: 57762427798

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Puratrophin 1 Polyclonal Antibody, 100ul Protein Analysis it alters splicing of CD45The pleckstrin homology and RhoGEF domain containing G4 encoded by PLEKHG4 can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants.

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Description

it alters splicing of CD45 (PTPRC

making it easy to ship and use

This gene was initially thought to be two different genes

the function of this protein remains to be elucidated

Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium

Puratrophin 1 Polyclonal Antibody, 100ul Protein Analysis it alters splicing of CD45The pleckstrin homology and RhoGEF domain containing G4 encoded by PLEKHG4 can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants.

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