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PHLP1 Polyclonal Antibody, 20ul PCR Series This protein also acts as

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PHLP1 Polyclonal Antibody, 20ul PCR Series This protein also acts asThis gene encodes a member of the serine threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt mediated insulin signaling.

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Description

This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans

PKP4 (Plakophilin 4) is a Protein Coding gene

The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin

Cowden syndrome

Activates procollagenase

PHLP1 Polyclonal Antibody, 20ul PCR Series This protein also acts asThis gene encodes a member of the serine threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt mediated insulin signaling.

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