ING4 Polyclonal Antibody, 50ul PCR Series Mitochondrial complex I deficiency is

Mitochondrial complex I deficiency is linked to myopathies

The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L)| which suggests the antiapoptotic function of this gene in cells

Engulfment and cell motility protein 1 interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration

function:Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro)

An important paralog of this gene is ZDHHC15

ING4 Polyclonal Antibody, 50ul PCR Series Mitochondrial complex I deficiency isING4 encodes a tumor suppressor protein that contains a PHD finger, which is a common motif in proteins involved in chromatin remodeling. Inhibitor of growth protein 4 can bind TP53 and EP300 p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53 dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.