Nibrin(Phospho Ser343) Polyclonal Antibody, 20ul Buffers & Solutions ADAM10 (ADAM metallopeptidase domain 10)

ADAM10 (ADAM metallopeptidase domain 10) encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse

Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor

Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix

Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position

Nibrin(Phospho Ser343) Polyclonal Antibody, 20ul Buffers & Solutions ADAM10 (ADAM metallopeptidase domain 10)Mutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint