PLC gamma1(Phospho Tyr1253) Polyclonal Antibody, 100ul Subcellular Fractions Most MS4A genes| including MS4A4E|

Most MS4A genes| including MS4A4E| encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons

Alternative splicing of downstream exons is also observed| which results in different forms of the stimulatory G-protein alpha subunit| a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses

The adhesion G protein-coupled receptor L2 participates in the regulation of exocytosis

which implicates this gene in determination of left-right asymmetric patterning

Alternatively spliced transcript variants encoding multiple isoforms have been observed for CASP2

PLC gamma1(Phospho Tyr1253) Polyclonal Antibody, 100ul Subcellular Fractions Most MS4A genes| including MS4A4E|The protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it