MEK-3(Phospho Ser218) Polyclonal Antibody, 100ul Peptide Synthesis Nitric oxide synthase 1 is

Nitric oxide synthase 1 is ubiquitously expressed

The protein localizes to the nucleoli and interacts with the U3 snoRNP complex

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

Pseudogenes of this gene have been identified on chromosome 5

Both proteins bind the p53 tumor suppressor protein and inhibit its activity

MEK-3(Phospho Ser218) Polyclonal Antibody, 100ul Peptide Synthesis Nitric oxide synthase 1 isThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase mediated signaling cascade. It phosphorylates and thus activates MAPK14 p38 MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the